Re-burying Artificially Exposed Surface of Viral Subunit Vaccines Through Oligomerization Enhances Vaccine Efficacy

Viral subunit vaccines often suffer low efficacy. We recently showed that when taken out of the context of whole virus particles, recombinant subunit vaccines contain artificially exposed surface regions that are non-neutralizing and reduce their efficacy, and thus these regions need to be re-buried...

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Detalles Bibliográficos
Autores principales: Han, Xuelian, Cai, Zhuming, Dai, Yulong, Huang, He, Cao, Xiangwen, Wang, Yuan, Fang, Yingying, Liu, Gang, Zhang, Min, Zhang, Yuhang, Yang, Binhui, Xue, Wei, Zhao, Guangyu, Tai, Wanbo, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278648/
https://www.ncbi.nlm.nih.gov/pubmed/35846760
http://dx.doi.org/10.3389/fcimb.2022.927674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278648/
https://www.ncbi.nlm.nih.gov/pubmed/35846760
http://dx.doi.org/10.3389/fcimb.2022.927674

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