Preliminary evaluation of a small interfering RNA molecular probe targeting murine double minute 2 in breast cancer

INTRODUCTION: Murine double minute 2 (MDM2) is an oncogene that is important in tumorigenesis, tumor metastasis and chemotherapy resistance. We aimed to synthesize a molecular imaging probe, (99m)Tc-HYNIC-siRNA 1489, which could specifically bind to MDM2. The [(99m)Tc]HYNIC-siRNA 1489 molecular prob...

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Detalles Bibliográficos
Autores principales: Wang, Xinyu, Xu, Peng, Jiao, Yuying, Luan, Sha, Gao, Yue, Zhao, Changjiu, Fu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278711/
https://www.ncbi.nlm.nih.gov/pubmed/35582848
http://dx.doi.org/10.1097/MNM.0000000000001582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278711/
https://www.ncbi.nlm.nih.gov/pubmed/35582848
http://dx.doi.org/10.1097/MNM.0000000000001582

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