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A pipeline for the reconstruction and evaluation of context-specific human metabolic models at a large-scale

Constraint-based (CB) metabolic models provide a mathematical framework and scaffold for in silico cell metabolism analysis and manipulation. In the past decade, significant efforts have been done to model human metabolism, enabled by the increased availability of multi-omics datasets and curated ge...

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Detalles Bibliográficos
Autores principales: Vieira, Vítor, Ferreira, Jorge, Rocha, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278738/
https://www.ncbi.nlm.nih.gov/pubmed/35749559
http://dx.doi.org/10.1371/journal.pcbi.1009294