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A pipeline for the reconstruction and evaluation of context-specific human metabolic models at a large-scale
Constraint-based (CB) metabolic models provide a mathematical framework and scaffold for in silico cell metabolism analysis and manipulation. In the past decade, significant efforts have been done to model human metabolism, enabled by the increased availability of multi-omics datasets and curated ge...
Autores principales: | Vieira, Vítor, Ferreira, Jorge, Rocha, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278738/ https://www.ncbi.nlm.nih.gov/pubmed/35749559 http://dx.doi.org/10.1371/journal.pcbi.1009294 |
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