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Integration of multidimensional splicing data and GWAS summary statistics for risk gene discovery

A common strategy for the functional interpretation of genome-wide association study (GWAS) findings has been the integrative analysis of GWAS and expression data. Using this strategy, many association methods (e.g., PrediXcan and FUSION) have been successful in identifying trait-associated genes vi...

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Detalles Bibliográficos
Autores principales: Ji, Ying, Wei, Qiang, Chen, Rui, Wang, Quan, Tao, Ran, Li, Bingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278751/
https://www.ncbi.nlm.nih.gov/pubmed/35771864
http://dx.doi.org/10.1371/journal.pgen.1009814