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Conformational Changes of Immobilized Polythymine due to External Stressors Studied with Temperature-Controlled Electrochemical Microdevices

[Image: see text] Conformational changes of single-stranded DNA (ssDNA) play an important role in a DNA strand’s ability to bind to target ligands. A variety of factors can influence conformation, including temperature, ionic strength, pH, buffer cation valency, strand length, and sequence. To bette...

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Detalles Bibliográficos
Autores principales: Vishnubhotla, Ramya, Montgomery, Christopher B., Steffens, Kristen L., Semancik, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278808/
https://www.ncbi.nlm.nih.gov/pubmed/33595321
http://dx.doi.org/10.1021/acs.langmuir.0c03219