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Comprehensive Analysis of Tryptic Peptides Arising from Disulfide Linkages in NISTmAb and Their Use for Developing a Mass Spectral Library

[Image: see text] This work presents methods for identifying and then creating a mass spectral library for disulfide-linked peptides originating from the NISTmAb, a reference material of the humanized IgG1k monoclonal antibody (RM 8671). Analyses involved both partially reduced and non-reduced sampl...

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Detalles Bibliográficos
Autores principales: Dong, Qian, Yan, Xinjian, Liang, Yuxue, Markey, Sanford P., Sheetlin, Sergey L., Remoroza, Concepcion A., Wallace, William E., Stein, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278810/
https://www.ncbi.nlm.nih.gov/pubmed/33555887
http://dx.doi.org/10.1021/acs.jproteome.0c00823