Cell disorientation by loss of SHH-dependent mechanosensation causes cyclopia

The physical causes of organ malformation remain largely unclear in most cases due to a lack of information on tissue/cell dynamics. Here, we address this issue by considering onset of cyclopia in sonic hedgehog (SHH)–inhibited chick embryos. We show that ventral forebrain–specific self-organization...

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Detalles Bibliográficos
Autores principales: Ohtsuka, Daisuke, Kida, Naoki, Lee, Sang-Woo, Kawahira, Naofumi, Morishita, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278851/
https://www.ncbi.nlm.nih.gov/pubmed/35857502
http://dx.doi.org/10.1126/sciadv.abn2330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278851/
https://www.ncbi.nlm.nih.gov/pubmed/35857502
http://dx.doi.org/10.1126/sciadv.abn2330

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