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Cell disorientation by loss of SHH-dependent mechanosensation causes cyclopia
The physical causes of organ malformation remain largely unclear in most cases due to a lack of information on tissue/cell dynamics. Here, we address this issue by considering onset of cyclopia in sonic hedgehog (SHH)–inhibited chick embryos. We show that ventral forebrain–specific self-organization...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278851/ https://www.ncbi.nlm.nih.gov/pubmed/35857502 http://dx.doi.org/10.1126/sciadv.abn2330 |