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Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activity

In the first meiotic cell division, proper segregation of chromosomes in most organisms depends on chiasmata, exchanges of continuity between homologous chromosomes that originate from the repair of programmed double-strand breaks (DSBs) catalyzed by the Spo11 endonuclease. Since DSBs can lead to ir...

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Detalles Bibliográficos
Autores principales: Guo, Heyun, Stamper, Ericca L, Sato-Carlton, Aya, Shimazoe, Masa A, Li, Xuan, Zhang, Liangyu, Stevens, Lewis, Tam, KC Jacky, Dernburg, Abby F, Carlton, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278955/
https://www.ncbi.nlm.nih.gov/pubmed/35758641
http://dx.doi.org/10.7554/eLife.77956