Disulfiram/Copper induces antitumor activity against gastric cancer via the ROS/MAPK and NPL4 pathways

Disulfiram (DSF) is an anti-alcoholism medication with superior antitumor activity and clinical safety; its antitumor mechanisms in gastric cancer (GC) have not been fully explored. In the present work, low nontoxic concentrations of copper (Cu) ions substantially enhanced DSF’s antitumor activity,...

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Detalles Bibliográficos
Autores principales: Liu, Yao, Guan, Xin, Wang, Meiling, Wang, Naixue, Chen, Yutong, Li, Baolei, Xu, Zhuxuan, Fu, Fangwei, Du, Cheng, Zheng, Zhendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278967/
https://www.ncbi.nlm.nih.gov/pubmed/35290151
http://dx.doi.org/10.1080/21655979.2022.2038434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278967/
https://www.ncbi.nlm.nih.gov/pubmed/35290151
http://dx.doi.org/10.1080/21655979.2022.2038434

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