Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway

The study aimed to explore the effects of local anesthetic bupivacaine on bladder cancer cells in vivo and in vitro. The cytotoxicity was detected by MTT assay. Apoptosis was measured by Hoechst 33342 staining and TUNEL. The contents of Fe(2+), Malondialdehyde (MDA), Glutathione (GSH) and reactive o...

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Detalles Bibliográficos
Autores principales: Hao, Jianli, Zhang, Weiqing, Huang, Zeqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278971/
https://www.ncbi.nlm.nih.gov/pubmed/35246010
http://dx.doi.org/10.1080/21655979.2022.2036909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278971/
https://www.ncbi.nlm.nih.gov/pubmed/35246010
http://dx.doi.org/10.1080/21655979.2022.2036909

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