Anti-CD44 and EGFR Dual-Targeted Solid Lipid Nanoparticles for Delivery of Doxorubicin to Triple-Negative Breast Cancer Cell Line: Preparation, Statistical Optimization, and In Vitro Characterization

BACKGROUND: Despite being more aggressive than other types of breast cancer, there is no suitable treatment for triple-negative breast cancer (TNBC). Here, we designed doxorubicin-containing solid lipid nanoparticles (SLNs) decorated with anti-EGFR/CD44 dual-RNA aptamers, which are overexpressed in...

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Detalles Bibliográficos
Autores principales: Darabi, Farnosh, Saidijam, Massoud, Nouri, Fatemeh, Mahjub, Reza, Soleimani, Meysam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279089/
https://www.ncbi.nlm.nih.gov/pubmed/35845934
http://dx.doi.org/10.1155/2022/6253978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279089/
https://www.ncbi.nlm.nih.gov/pubmed/35845934
http://dx.doi.org/10.1155/2022/6253978

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