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Mediation of the APOE Associations With Cognition Through Cerebral Blood Flow: The CIBL Study

BACKGROUND: The ε4 allele of the apolipoprotein E (APOE) gene is a strong genetic risk factor for aging-related cognitive decline. However, the causal connection between ε4 alleles and cognition is not well understood. The objective of this study was to identify the roles of cerebral blood flow (CBF...

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Detalles Bibliográficos
Autores principales: Wang, Yan-Li, Sun, Mengfan, Wang, Fang-Ze, Wang, Xiaohong, Jia, Ziyan, Zhang, Yuan, Li, Runzhi, Jiang, Jiwei, Wang, Linlin, Li, Wenyi, Sun, Yongan, Chen, Jinglong, Zhang, Cuicui, Shi, Baolin, Liu, Jianjian, Liu, Xiangrong, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279129/
https://www.ncbi.nlm.nih.gov/pubmed/35847686
http://dx.doi.org/10.3389/fnagi.2022.928925