Structural insights into dsRNA processing by Drosophila Dicer-2–Loqs-PD

Small interfering RNAs (siRNAs) are the key components for RNA interference (RNAi), a conserved RNA-silencing mechanism in many eukaryotes(1,2). In Drosophila, an RNase III enzyme Dicer-2 (Dcr-2), aided by its cofactor Loquacious-PD (Loqs-PD), has an important role in generating 21 bp siRNA duplexes...

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Detalles Bibliográficos
Autores principales: Su, Shichen, Wang, Jia, Deng, Ting, Yuan, Xun, He, Jinqiu, Liu, Nan, Li, Xiaomin, Huang, Ying, Wang, Hong-Wei, Ma, Jinbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279154/
https://www.ncbi.nlm.nih.gov/pubmed/35768513
http://dx.doi.org/10.1038/s41586-022-04911-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279154/
https://www.ncbi.nlm.nih.gov/pubmed/35768513
http://dx.doi.org/10.1038/s41586-022-04911-x

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