Transition between conformational states of the TREK-1 K2P channel promoted by interaction with PIP(2)

Members of the TREK family of two-pore domain potassium channels are highly sensitive to regulation by membrane lipids, including phosphatidylinositol-4,5-bisphosphate (PIP(2)). Previous studies have demonstrated that PIP(2) increases TREK-1 channel activity; however, the mechanistic understanding o...

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Detalles Bibliográficos
Autores principales: Panasawatwong, Adisorn, Pipatpolkai, Tanadet, Tucker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279171/
https://www.ncbi.nlm.nih.gov/pubmed/35596528
http://dx.doi.org/10.1016/j.bpj.2022.05.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279171/
https://www.ncbi.nlm.nih.gov/pubmed/35596528
http://dx.doi.org/10.1016/j.bpj.2022.05.019

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