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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Co-fractionation/mass spectrometry (CF/MS) enables the mapping of endogenous macromolecular networks on a proteome scale, but current methods are experimentally laborious, resource intensive and afford lesser quantitative accuracy. Here, we present a technically efficient, cost-effective and reprodu...

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Detalles Bibliográficos
Autores principales: Havugimana, Pierre C., Goel, Raghuveera Kumar, Phanse, Sadhna, Youssef, Ahmed, Padhorny, Dzmitry, Kotelnikov, Sergei, Kozakov, Dima, Emili, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279285/
https://www.ncbi.nlm.nih.gov/pubmed/35831314
http://dx.doi.org/10.1038/s41467-022-31809-z