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CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection

HIV persistence in tissue sites despite ART is a major barrier to HIV cure. Detailed studies of HIV-infected cells and immune responses in native lymph node tissue environment is critical for gaining insight into immune mechanisms impacting HIV persistence and clearance in tissue sanctuary sites. We...

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Detalles Bibliográficos
Autores principales: Baiyegunhi, Omolara O., Mann, Jaclyn, Khaba, Trevor, Nkosi, Thandeka, Mbatha, Anele, Ogunshola, Funsho, Chasara, Caroline, Ismail, Nasreen, Ngubane, Thandekile, Jajbhay, Ismail, Pansegrouw, Johan, Dong, Krista L., Walker, Bruce D., Ndung’u, Thumbi, Ndhlovu, Zaza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279299/
https://www.ncbi.nlm.nih.gov/pubmed/35831418
http://dx.doi.org/10.1038/s41467-022-31692-8