Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethality

Renal cell carcinoma (RCC) is a common malignant tumor in the world. Histologically, most of RCC is classified as clear cell renal cell carcinoma (ccRCC), which is the most prevalent subtype. The overall survival of patients with ccRCC is poor, thus it is urgent to further explore its mechanism and...

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Detalles Bibliográficos
Autores principales: Li, Pu, Chen, Tingting, Kuang, Peng, Liu, Fujun, Li, Zhongmin, Liu, Fangfang, Wang, Yu, Zhang, Wenfeng, Cai, Xiuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279325/
https://www.ncbi.nlm.nih.gov/pubmed/35831273
http://dx.doi.org/10.1038/s41419-022-04973-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279325/
https://www.ncbi.nlm.nih.gov/pubmed/35831273
http://dx.doi.org/10.1038/s41419-022-04973-9

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