Conserved Cdk inhibitors show unique structural responses to tyrosine phosphorylation

Balanced proliferation-quiescence decisions are vital during normal development and in tissue homeostasis, and their dysregulation underlies tumorigenesis. Entry into proliferative cycles is driven by Cyclin/Cyclin-dependent kinases (Cdks). Conserved Cdk inhibitors (CKIs) p21(Cip1/Waf1), p27(Kip1),...

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Detalles Bibliográficos
Autores principales: Swadling, Jacob B., Warnecke, Tobias, Morris, Kyle L., Barr, Alexis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279356/
https://www.ncbi.nlm.nih.gov/pubmed/35614852
http://dx.doi.org/10.1016/j.bpj.2022.05.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279356/
https://www.ncbi.nlm.nih.gov/pubmed/35614852
http://dx.doi.org/10.1016/j.bpj.2022.05.024

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