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Conserved Cdk inhibitors show unique structural responses to tyrosine phosphorylation

Balanced proliferation-quiescence decisions are vital during normal development and in tissue homeostasis, and their dysregulation underlies tumorigenesis. Entry into proliferative cycles is driven by Cyclin/Cyclin-dependent kinases (Cdks). Conserved Cdk inhibitors (CKIs) p21(Cip1/Waf1), p27(Kip1),...

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Detalles Bibliográficos
Autores principales:	Swadling, Jacob B., Warnecke, Tobias, Morris, Kyle L., Barr, Alexis R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279356/ https://www.ncbi.nlm.nih.gov/pubmed/35614852 http://dx.doi.org/10.1016/j.bpj.2022.05.024

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