Loop-extrusion and polymer phase-separation can co-exist at the single-molecule level to shape chromatin folding

Loop-extrusion and phase-separation have been proposed as mechanisms that shape chromosome spatial organization. It is unclear, however, how they perform relative to each other in explaining chromatin architecture data and whether they compete or co-exist at the single-molecule level. Here, we compa...

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Detalles Bibliográficos
Autores principales: Conte, Mattia, Irani, Ehsan, Chiariello, Andrea M., Abraham, Alex, Bianco, Simona, Esposito, Andrea, Nicodemi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279381/
https://www.ncbi.nlm.nih.gov/pubmed/35831310
http://dx.doi.org/10.1038/s41467-022-31856-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279381/
https://www.ncbi.nlm.nih.gov/pubmed/35831310
http://dx.doi.org/10.1038/s41467-022-31856-6

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