Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1

Osteoarthritis (OA) is a prevalent joint disease with no effective treatment strategies. Aberrant mechanical stimuli was demonstrated to be an essential factor for OA pathogenesis. Although multiple studies have detected potential regulatory mechanisms underlying OA and have concentrated on developi...

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Detalles Bibliográficos
Autores principales: Jin, Yu, Liu, Zhen, Li, Zhenxia, Li, Hairui, Zhu, Cheng, Li, Ruomei, Zhou, Ting, Fang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279410/
https://www.ncbi.nlm.nih.gov/pubmed/35831280
http://dx.doi.org/10.1038/s41368-022-00190-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279410/
https://www.ncbi.nlm.nih.gov/pubmed/35831280
http://dx.doi.org/10.1038/s41368-022-00190-4

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