Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis

The underlying mechanism by which growth factor receptor-bound protein 2 (Grb2) regulates necroptosis remains unexplored. In the present study, we found that rasfonin, a fungal natural product and an activator of necroptosis, enhanced Grb2 binding to receptor-interacting serine/threonine kinase 1 (R...

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Detalles Bibliográficos
Autores principales: Hou, Bolin, Huang, Haiwen, Li, Yueqian, Liang, Jingnan, Xi, Zhijun, Jiang, Xuejun, Liu, Ling, Li, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279413/
https://www.ncbi.nlm.nih.gov/pubmed/35831301
http://dx.doi.org/10.1038/s41420-022-01106-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279413/
https://www.ncbi.nlm.nih.gov/pubmed/35831301
http://dx.doi.org/10.1038/s41420-022-01106-1

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