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Genetic variations in methotrexate metabolic pathway genes influence methotrexate responses in rheumatoid arthritis patients in Malaysia

Methotrexate (MTX) is the most widely used disease-modifying anti-rheumatic drug (DMARD) for rheumatoid arthritis (RA). Many studies have attempted to understand the genetic risk factors that affect the therapeutic outcomes in RA patients treated with MTX. Unlike other studies that focus on the popu...

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Detalles Bibliográficos
Autores principales: Sha, Hong Xi, Veerapen, Kumar, Chow, Sook Khuan, Gun, Suk Chyn, Lau, Ing Soo, Lim, Renee Lay Hong, Zulkifli, Zaliha, Yow, Yoon-Yen, Peh, Suat Cheng, Hwang, Jung Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279481/
https://www.ncbi.nlm.nih.gov/pubmed/35831345
http://dx.doi.org/10.1038/s41598-022-15991-0