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Genetic variations in methotrexate metabolic pathway genes influence methotrexate responses in rheumatoid arthritis patients in Malaysia
Methotrexate (MTX) is the most widely used disease-modifying anti-rheumatic drug (DMARD) for rheumatoid arthritis (RA). Many studies have attempted to understand the genetic risk factors that affect the therapeutic outcomes in RA patients treated with MTX. Unlike other studies that focus on the popu...
Autores principales: | Sha, Hong Xi, Veerapen, Kumar, Chow, Sook Khuan, Gun, Suk Chyn, Lau, Ing Soo, Lim, Renee Lay Hong, Zulkifli, Zaliha, Yow, Yoon-Yen, Peh, Suat Cheng, Hwang, Jung Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279481/ https://www.ncbi.nlm.nih.gov/pubmed/35831345 http://dx.doi.org/10.1038/s41598-022-15991-0 |
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