Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope

We studied the prevalent cytotoxic CD8 T cell response mounted against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike glycoprotein(269-277) epitope (sequence YLQPRTFLL) via the most frequent human leukocyte antigen (HLA) class I worldwide, HLA A(∗)02. The Spike P272L mutation tha...

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Detalles Bibliográficos
Autores principales: Dolton, Garry, Rius, Cristina, Hasan, Md Samiul, Wall, Aaron, Szomolay, Barbara, Behiry, Enas, Whalley, Thomas, Southgate, Joel, Fuller, Anna, Morin, Théo, Topley, Katie, Tan, Li Rong, Goulder, Philip J.R., Spiller, Owen B., Rizkallah, Pierre J., Jones, Lucy C., Connor, Thomas R., Sewell, Andrew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279490/
https://www.ncbi.nlm.nih.gov/pubmed/35931021
http://dx.doi.org/10.1016/j.cell.2022.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279490/
https://www.ncbi.nlm.nih.gov/pubmed/35931021
http://dx.doi.org/10.1016/j.cell.2022.07.002

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