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BRAF V600E protect from cell death via inhibition of the mitochondrial permeability transition in papillary and anaplastic thyroid cancers

BRAF T1799A mutation is the most common genetic variation in thyroid cancer, resulting in the production of BRAF V600E mutant protein reported to make cells resistant to apoptosis. However, the mechanism by which BRAF V600E regulates cell death remains unknown. We constructed BRAF V600E overexpressi...

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Detalles Bibliográficos
Autores principales: Gao, Yanyan, Zhang, Deyu, Wang, Fei, Zhang, Dejiu, Li, Peifeng, Wang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279591/
https://www.ncbi.nlm.nih.gov/pubmed/35748101
http://dx.doi.org/10.1111/jcmm.17443