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STAT3 suppresses the AMPKα/ULK1‐dependent induction of autophagy in glioblastoma cells

Despite advances in molecular characterization, glioblastoma (GBM) remains the most common and lethal brain tumour with high mortality rates in both paediatric and adult patients. The signal transducer and activator of transcription 3 (STAT3) is an important oncogenic driver of GBM. Although STAT3 r...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Sujoy, Yin, Jinggang, Yang, Chuanhe, Wang, Yinan, Sims, Michelle, Pfeffer, Lawrence M., Chaum, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279602/
https://www.ncbi.nlm.nih.gov/pubmed/35670018
http://dx.doi.org/10.1111/jcmm.17421