RAC3 Inhibition Induces Autophagy to Impair Metastasis in Bladder Cancer Cells via the PI3K/AKT/mTOR Pathway

BACKGROUND: Bladder cancer (BCa) is one of the most frequent malignant tumors globally, with a significant morbidity and mortality rate. Gene expression dysregulation has been proven to play a critical role in tumorigenesis. Ras-related C3 botulinum toxin substrate3 (RAC3), which is overexpressed in...

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Detalles Bibliográficos
Autores principales: Wang, Liwei, Shi, Jiazhong, Liu, Sha, Huang, Yaqin, Ding, Hua, Zhao, Baixiong, Liu, Yuting, Wang, Wuxing, Yang, Jin, Chen, Zhiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279623/
https://www.ncbi.nlm.nih.gov/pubmed/35847878
http://dx.doi.org/10.3389/fonc.2022.915240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279623/
https://www.ncbi.nlm.nih.gov/pubmed/35847878
http://dx.doi.org/10.3389/fonc.2022.915240

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