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Disruption of adipocyte HIF-1α improves atherosclerosis through the inhibition of ceramide generation
Atherosclerosis is a chronic multifactorial cardiovascular disease. Western diets have been reported to affect atherosclerosis through regulating adipose function. In high cholesterol diet-fed ApoE(–/–) mice, adipocyte HIF-1α deficiency or direct inhibition of HIF-1α by the selective pharmacological...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279628/ https://www.ncbi.nlm.nih.gov/pubmed/35847503 http://dx.doi.org/10.1016/j.apsb.2021.10.001 |