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Disruption of adipocyte HIF-1α improves atherosclerosis through the inhibition of ceramide generation

Atherosclerosis is a chronic multifactorial cardiovascular disease. Western diets have been reported to affect atherosclerosis through regulating adipose function. In high cholesterol diet-fed ApoE(–/–) mice, adipocyte HIF-1α deficiency or direct inhibition of HIF-1α by the selective pharmacological...

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Detalles Bibliográficos
Autores principales: Wang, Pengcheng, Zeng, Guangyi, Yan, Yu, Zhang, Song-yang, Dong, Yongqiang, Zhang, Yangming, Zhang, Xingzhong, Liu, Huiying, Zhang, Zhipeng, Jiang, Changtao, Pang, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279628/
https://www.ncbi.nlm.nih.gov/pubmed/35847503
http://dx.doi.org/10.1016/j.apsb.2021.10.001

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