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Unraveling the drug distribution in brain enabled by MALDI MS imaging with laser-assisted chemical transfer
Accurate localization of central nervous system (CNS) drug distribution in the brain is quite challenging to matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI), owing to the ionization competition/suppression of highly abundant endogenous biomolecules and MALDI matri...
Autores principales: | Guo, Shuai, Li, Kening, Chen, Yanwen, Li, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279630/ https://www.ncbi.nlm.nih.gov/pubmed/35847487 http://dx.doi.org/10.1016/j.apsb.2021.11.007 |
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