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Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles

Alzheimer's disease (AD) is a prevalent and deleterious neurodegenerative disorder characterized by an irreversible and progressive impairment of cognitive abilities as well as the formation of amyloid β (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. By far, the precise mechanism...

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Detalles Bibliográficos
Autores principales: Deng, Zhiqiang, Dong, Yu, Zhou, Xiaoting, Lu, Jia-Hong, Yue, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279633/
https://www.ncbi.nlm.nih.gov/pubmed/35847516
http://dx.doi.org/10.1016/j.apsb.2021.12.009