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Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
Alzheimer's disease (AD) is a prevalent and deleterious neurodegenerative disorder characterized by an irreversible and progressive impairment of cognitive abilities as well as the formation of amyloid β (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. By far, the precise mechanism...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279633/ https://www.ncbi.nlm.nih.gov/pubmed/35847516 http://dx.doi.org/10.1016/j.apsb.2021.12.009 |