Glutor, a Glucose Transporter Inhibitor, Exerts Antineoplastic Action on Tumor Cells of Thymic Origin: Implication of Modulated Metabolism, Survival, Oxidative Stress, Mitochondrial Membrane Potential, pH Homeostasis, and Chemosensitivity

Neoplastic cells overexpress glucose transporters (GLUT), particularly GLUT1 and GLUT3, to support altered metabolism. Hence, novel strategies are being explored to effectively inhibit GLUTs for a daunting interference of glucose uptake. Glutor, a piperazine-2-one derivative, is a newly reported pan...

Descripción completa

Detalles Bibliográficos
Autores principales: Temre, Mithlesh Kumar, Yadav, Saveg, Goel, Yugal, Pandey, Shrish Kumar, Kumar, Ajay, Singh, Sukh Mahendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279700/
https://www.ncbi.nlm.nih.gov/pubmed/35847943
http://dx.doi.org/10.3389/fonc.2022.925666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279700/
https://www.ncbi.nlm.nih.gov/pubmed/35847943
http://dx.doi.org/10.3389/fonc.2022.925666

Ejemplares similares