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Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection

The treatment of Alzheimer's disease (AD) is one of the most difficult challenges in neurodegenerative diseases due to the insufficient blood‒brain barrier (BBB) permeability and unsatisfactory intra-brain distribution of drugs. Therefore, we established an ibuprofen and FK506 encapsulated drug...

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Detalles Bibliográficos
Autores principales: He, Xueqin, Wang, Xiaorong, Yang, Lianyi, Yang, Zhihang, Yu, Wenqi, Wang, Yazhen, Liu, Rui, Chen, Meiwan, Gao, Huile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279705/
https://www.ncbi.nlm.nih.gov/pubmed/35847512
http://dx.doi.org/10.1016/j.apsb.2022.02.001