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The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles

The presence of protein corona on the surface of nanoparticles modulates their physiological interactions such as cellular association and targeting property. It has been shown that α-mangostin (αM)-loaded poly(ethylene glycol)-poly(l-lactide) (PEG-PLA) nanoparticles (NP-αM) specifically increased l...

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Detalles Bibliográficos
Autores principales: Tang, Yuyun, Gao, Jinchao, Wang, Tao, Zhang, Qian, Wang, Antian, Huang, Meng, Yu, Renhe, Chen, Hongzhuan, Gao, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279712/
https://www.ncbi.nlm.nih.gov/pubmed/35847504
http://dx.doi.org/10.1016/j.apsb.2021.09.029