Cargando…

The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles

The presence of protein corona on the surface of nanoparticles modulates their physiological interactions such as cellular association and targeting property. It has been shown that α-mangostin (αM)-loaded poly(ethylene glycol)-poly(l-lactide) (PEG-PLA) nanoparticles (NP-αM) specifically increased l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Yuyun, Gao, Jinchao, Wang, Tao, Zhang, Qian, Wang, Antian, Huang, Meng, Yu, Renhe, Chen, Hongzhuan, Gao, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279712/ https://www.ncbi.nlm.nih.gov/pubmed/35847504 http://dx.doi.org/10.1016/j.apsb.2021.09.029

Ejemplares similares

Evaluation of self-assembled HCPT-loaded PEG-b-PLA nanoparticles by comparing with HCPT-loaded PLA nanoparticles
por: Yang, Xiangrui, et al.
Publicado: (2014)

Arenobufagin-loaded PEG-PLA nanoparticles for reducing toxicity and enhancing cancer therapy
por: Jiaying, Yang, et al.
Publicado: (2023)

mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)
por: Ghasemi, Rohollah, et al.
Publicado: (2018)

Local delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs
por: Yao, Wenxin, et al.
Publicado: (2014)

Design, Synthesis, and Comparison of PLA-PEG-PLA and PEG-PLA-PEG Copolymers for Curcumin Delivery to Cancer Cells
por: Rostami, Neda, et al.
Publicado: (2023)

Author Correction: mPEG-PLA and PLA-PEG-PLA nanoparticles as new carriers for delivery of recombinant human Growth Hormone (rhGH)
por: Ghasemi, Rohollah, et al.
Publicado: (2019)

Synthesis of protein-coated biocompatible methotrexate-loaded PLA-PEG-PLA nanoparticles for breast cancer treatment
por: Massadeh, Salam, et al.
Publicado: (2016)

Preparation and Characterization of Cationic PLA-PEG Nanoparticles for Delivery of Plasmid DNA
por: Zou, Weiwei, et al.
Publicado: (2009)

Recent advances in PEG–PLA block copolymer nanoparticles
por: Xiao, Ren Zhong, et al.
Publicado: (2010)

Nano‐Brake Halts Mitochondrial Dysfunction Cascade to Alleviate Neuropathology and Rescue Alzheimer's Cognitive Deficits
por: Zhang, Qian, et al.
Publicado: (2023)

Development of Epirubicin-Loaded Biocompatible Polymer PLA–PEG–PLA Nanoparticles: Synthesis, Characterization, Stability, and In Vitro Anticancerous Assessment
por: Massadeh, Salam, et al.
Publicado: (2021)

Chitosan Hydrogel Doped with PEG-PLA Nanoparticles for the Local Delivery of miRNA-146a to Treat Allergic Rhinitis
por: Su, Yu, et al.
Publicado: (2020)

Docetaxel loaded mPEG-PLA nanoparticles for sarcoma therapy: preparation, characterization, pharmacokinetics, and anti-tumor efficacy
por: Chen, Jianhua, et al.
Publicado: (2021)

Preparation and Characterization of PLA-PEG-PLA/PEI/DNA Nanoparticles for Improvement of Transfection Efficiency and Controlled Release of DNA in Gene Delivery Systems
por: Amani, Amin, et al.
Publicado: (2019)

Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines
por: Alyafee, Yusra A, et al.
Publicado: (2017)

The Yin and Yang of the protein corona on the delivery journey of nanoparticles
por: Wang, Yi-Feng, et al.
Publicado: (2022)

Anti-transferrin receptor-modified amphotericin B-loaded PLA–PEG nanoparticles cure Candidal meningitis and reduce drug toxicity
por: Tang, Xiaolong, et al.
Publicado: (2015)

Anticancer Biosurfactant-Loaded PLA–PEG Nanoparticles Induce Apoptosis in Human MDA-MB-231 Breast Cancer Cells
por: Wadhawan, Aishani, et al.
Publicado: (2022)

Cell-Penetrating Peptide Modified PEG-PLA Micelles for Efficient PTX Delivery
por: Shuai, Qi, et al.
Publicado: (2020)

Prolonged Release and Functionality of Interleukin-10 Encapsulated within PLA-PEG Nanoparticles
por: Duncan, Skyla A., et al.
Publicado: (2019)

Adenosine-Functionalized Biodegradable PLA-b-PEG Nanoparticles Ameliorate Osteoarthritis in Rats
por: Liu, Xiuling, et al.
Publicado: (2019)

Lactoferrin-Loaded PEG/PLA Block Copolymer Targeted With Anti-Transferrin Receptor Antibodies for Alzheimer Disease
por: Li, Guichen, et al.
Publicado: (2020)

PLA-PEG Implant as a Drug Delivery System in Glaucoma Surgery: Experimental Study
por: Germanova, Viktoriya N., et al.
Publicado: (2022)

Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity
por: Andima, Moses, et al.
Publicado: (2018)

Drug-loaded PEG-PLGA nanoparticles for cancer treatment
por: Zhang, Dan, et al.
Publicado: (2022)

mPEG-PLA/TPGS mixed micelles via intranasal administration improved the bioavailability of lamotrigine in the hippocampus
por: Yu, Anan, et al.
Publicado: (2017)

Oligo(Lactic Acid)(8)-Docetaxel Prodrug-Loaded PEG-b-PLA Micelles for Prostate Cancer
por: Repp, Lauren, et al.
Publicado: (2021)

Smart PEG-Block-PLA/PLA Nanosystems: Impact of the Characteristics of the Polymer Blend on the Redox Responsiveness
por: Van Gheluwe, Louise, et al.
Publicado: (2023)

Evaluation of Ibuprofen Prolonged Release of Biomedical PLA-PEG-PLA Hydrogel via Degradation Mechanism
por: Nguyen, Hien Thi-Thanh, et al.
Publicado: (2023)

Novel PEG-graft-PLA nanoparticles with the potential for encapsulation and controlled release of hydrophobic and hydrophilic medications in aqueous medium
por: Wang, Bin, et al.
Publicado: (2011)

Curcumin-Loaded PLA Nanoparticles: Formulation and Physical Evaluation
por: Rachmawati, Heni, et al.
Publicado: (2016)

Preparation and In Vitro Release of Total Alkaloids from Alstonia Scholaris Leaves Loaded mPEG-PLA Microspheres
por: Zheng, Xiangyu, et al.
Publicado: (2019)

pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma
por: Householder, Kyle T., et al.
Publicado: (2018)

Surface charge modulation of rifampicin-loaded PLA nanoparticles to improve antibiotic delivery in Staphylococcus aureus biofilms
por: Da Costa, David, et al.
Publicado: (2021)

Doxorubicin-conjugated PLA-PEG-Folate based polymeric micelle for tumor-targeted delivery: Synthesis and in vitro evaluation
por: Hami, Zahra, et al.
Publicado: (2014)

Gefitinib conjugated PEG passivated graphene quantum dots incorporated PLA microspheres for targeted anticancer drug delivery
por: Gautam, Abhishek, et al.
Publicado: (2022)

Preparation and Evaluation of Doxorubicin-Loaded PLA–PEG–FA Copolymer Containing Superparamagnetic Iron Oxide Nanoparticles (SPIONs) for Cancer Treatment: Combination Therapy with Hyperthermia and Chemotherapy
por: Khaledian, Mohammad, et al.
Publicado: (2020)

Heparin-Tagged PLA-PEG Copolymer-Encapsulated Biochanin A-Loaded (Mg/Al) LDH Nanoparticles Recommended for Non-Thrombogenic and Anti-Proliferative Stent Coating
por: Adepu, Shivakalyani, et al.
Publicado: (2021)

New Method to Prepare Mitomycin C Loaded PLA-Nanoparticles with High Drug Entrapment Efficiency
por: Hou, Zhenqing, et al.
Publicado: (2009)

Three-Step Synthesis of a Redox-Responsive Blend of PEG–block–PLA and PLA and Application to the Nanoencapsulation of Retinol
por: Van Gheluwe, Louise, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e12cbpjdoq3lhpbqfg0uhpgoqv