High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS

Discovery of drugs rapidly and effectively is an important aspect for Alzheimer's disease (AD). In this study, a novel high-throughput screening (HTS) method aims at screening the small-molecules with amyloid-β (Aβ) binding affinity from natural medicines, based on the combinational use of biol...

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Detalles Bibliográficos
Autores principales: Guo, Minsong, Zhu, Fengdan, Qiu, Wenqiao, Qiao, Gan, Law, Betty Yuen-Kwan, Yu, Lu, Wu, Jianming, Tang, Yong, Yu, Chonglin, Qin, Dalian, Zhou, Xiaogang, Wu, Anguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279722/
https://www.ncbi.nlm.nih.gov/pubmed/35847494
http://dx.doi.org/10.1016/j.apsb.2021.08.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279722/
https://www.ncbi.nlm.nih.gov/pubmed/35847494
http://dx.doi.org/10.1016/j.apsb.2021.08.030

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