Cargando…

High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS

Discovery of drugs rapidly and effectively is an important aspect for Alzheimer's disease (AD). In this study, a novel high-throughput screening (HTS) method aims at screening the small-molecules with amyloid-β (Aβ) binding affinity from natural medicines, based on the combinational use of biol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Minsong, Zhu, Fengdan, Qiu, Wenqiao, Qiao, Gan, Law, Betty Yuen-Kwan, Yu, Lu, Wu, Jianming, Tang, Yong, Yu, Chonglin, Qin, Dalian, Zhou, Xiaogang, Wu, Anguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279722/ https://www.ncbi.nlm.nih.gov/pubmed/35847494 http://dx.doi.org/10.1016/j.apsb.2021.08.030

Ejemplares similares

The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis
por: Yu, Lu, et al.
Publicado: (2019)

Kinetic Titration Series with Biolayer Interferometry
por: Frenzel, Daniel, et al.
Publicado: (2014)

Biolayer interferometry for DNA-protein interactions
por: Barrows, John K., et al.
Publicado: (2022)

A Rapid and Sensitive UHPLC–MS/MS Method for Determination of Chlorogenic Acid and Its Application to Distribution and Neuroprotection in Rat Brain
por: Bai, Chongfei, et al.
Publicado: (2023)

Simultaneous Determination of Structurally Diverse Compounds in Different Fangchi Species by UHPLC-DAD and UHPLC-ESI-MS/MS
por: Sim, Hee-Jung, et al.
Publicado: (2013)

Pharmacokinetics and Metabolism Study of Deep-Sea-Derived Butyrolactone I in Rats by UHPLC–MS/MS and UHPLC–Q-TOF-MS
por: Wu, Liang, et al.
Publicado: (2021)

Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins
por: Wu, An-Guo, et al.
Publicado: (2015)

Characterization of antibody-antigen interactions using biolayer interferometry
por: Noy-Porat, Tal, et al.
Publicado: (2021)

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Detection and determination of undeclared synthetic caffeine in weight loss formulations using HPLC-DAD and UHPLC-MS/MS
por: Viana, Carine, et al.
Publicado: (2018)

Identification of Metabolites of Eupatorin in Vivo and in Vitro Based on UHPLC-Q-TOF-MS/MS
por: Li, Luya, et al.
Publicado: (2019)

Determination of Alkaloids and Flavonoids in Sophora flavescens by UHPLC-Q-TOF/MS
por: Dong, Yaqian, et al.
Publicado: (2021)

Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS
por: Bai, Yang, et al.
Publicado: (2018)

Influenza vaccine titer determination using biolayer interferometry (BLI)
por: Wheatley, David W, et al.
Publicado: (2015)

Measuring the effects of macromolecular crowding on antibody function with biolayer interferometry
por: Kim, Dorothy M., et al.
Publicado: (2019)

Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS
por: He, Yan, et al.
Publicado: (2022)

Characterization and Quantification of Nonanthocyanin Phenolic Compounds in White and Blue Bilberry (Vaccinium myrtillus) Juices and Wines Using UHPLC-DAD−ESI-QTOF-MS and UHPLC-DAD
por: Liu, Shuxun, et al.
Publicado: (2020)

Metabolite Identification of Isopropoxy Benzene Guanidine in Rat Liver Microsomes by Using UHPLC-Q-TOF-MS/MS
por: Lu, Yixing, et al.
Publicado: (2023)

On-Site Biolayer Interferometry-Based Biosensing of Carbamazepine in Whole Blood of Epileptic Patients
por: Bian, Sumin, et al.
Publicado: (2021)

Identification for metabolism profiles and pharmacokinetic studies of tradition Chinese prescription Ji-Ming-San and its major metabolites in rats by UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS
por: Hsieh, Cheng-Yang, et al.
Publicado: (2023)

Screening and Identification of the Main Metabolites of Schisantherin a In Vivo and In Vitro by Using UHPLC-Q-TOF-MS/MS
por: Feng, Wei, et al.
Publicado: (2020)

A Study of the Identification, Fragmentation Mode and Metabolic Pathways of Imatinib in Rats Using UHPLC-Q-TOF-MS/MS
por: Liu, Sijiang, et al.
Publicado: (2021)

Applications of Surface Plasmon Resonance and Biolayer Interferometry for Virus–Ligand Binding
por: Murali, Shruthi, et al.
Publicado: (2022)

Studies on the metabolism and degradation of vancomycin in simulated in vitro and aquatic environment by UHPLC-Triple-TOF-MS/MS
por: Cao, Mengsi, et al.
Publicado: (2018)

UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam
por: Pham, Hong Ngoc, et al.
Publicado: (2022)

On-line identification of the chemical constituents of Polygoni Multiflori Radix by UHPLC-Q-ToF MS/MS
por: Wang, Xueting, et al.
Publicado: (2023)

Chemical Profiling of an Antimigraine Herbal Preparation, Tianshu Capsule, Based on the Combination of HPLC, LC-DAD-MS(n), and LC-DAD-ESI-IT-TOF/MS Analyses
por: Liang, Juanjuan, et al.
Publicado: (2014)

Comparative Study for the Determination of Fat-Soluble Vitamins in Rice Cereal Baby Foods Using HPLC-DAD and UHPLC-APCI-MS/MS
por: Katsa, Maria, et al.
Publicado: (2021)

Simultaneous Qualitative and Quantitative Evaluation of the Coptidis Rhizoma and Euodiae Fructus Herbal Pair by Using UHPLC-ESI-QTOF-MS and UHPLC-DAD
por: Li, Yan-Ying, et al.
Publicado: (2020)

Antiliver Fibrosis Screening of Active Ingredients from Apium graveolens L. Seeds via GC-TOF-MS and UHPLC-MS/MS
por: Qiao, Ming, et al.
Publicado: (2020)

Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry
por: Dzimianski, John V., et al.
Publicado: (2020)

Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry
por: Dzimianski, John V., et al.
Publicado: (2020)

Suppressing Nonspecific Binding in Biolayer Interferometry Experiments for Weak Ligand–Analyte Interactions
por: Dubrow, Alyssa, et al.
Publicado: (2022)

Qualification of a Biolayer Interferometry Assay to Support AZD7442 Resistance Monitoring
por: Brady, Tyler, et al.
Publicado: (2022)

Rapid Identification of Berberine Metabolites in Rat Plasma by UHPLC-Q-TOF-MS
por: Xu, Peng, et al.
Publicado: (2019)

Metabolite Profiling of Meridianin C In Vivo of Rat by UHPLC/Q-TOF MS
por: Zhang, Guozhe, et al.
Publicado: (2021)

Analysis of In Vivo Existence Forms of Nardosinone in Mice by UHPLC-Q-TOF-MS Technique
por: Zhang, Jing, et al.
Publicado: (2022)

Chemical Discrimination of Astragalus mongholicus and Astragalus membranaceus Based on Metabolomics Using UHPLC-ESI-Q-TOF-MS/MS Approach
por: Wang, Yumei, et al.
Publicado: (2019)

Mediterranean Propolis from the Adriatic Sea Islands as a Source of Natural Antioxidants: Comprehensive Chemical Biodiversity Determined by GC-MS, FTIR-ATR, UHPLC-DAD-QqTOF-MS, DPPH and FRAP Assay
por: Svečnjak, Lidija, et al.
Publicado: (2020)

Corrigendum to “Antiliver Fibrosis Screening of Active Ingredients from Apium graveolens L. Seeds via GC-TOF-MS and UHPLC-MS/MS”
por: Qiao, Ming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rak7vqc3321tamt9l6u4e1ebo9