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Down-regulation of LCN2 attenuates retinal vascular dysfunction and caspase-1-mediated pyroptosis in diabetes mellitus

BACKGROUND: Diabetic retinopathy (DR) is a diabetic microangiopathy with increasing incidence, which seriously threatens the quality of life of patients. This study investigated the molecular regulation mechanism of lipocalin-2 (LCN2) in DR by targeting the function of human retinal vascular endothe...

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Detalles Bibliográficos
Autores principales: Su, Xingjie, Zhou, Pingping, Qi, Yanxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279825/
https://www.ncbi.nlm.nih.gov/pubmed/35845521
http://dx.doi.org/10.21037/atm-22-2655