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MicroRNA-206 promotes the recruitment of CD8(+) T cells by driving M1 polarisation of Kupffer cells

OBJECTIVE: Kupffer cells (KCs) protect against hepatocellular carcinoma (HCC) by communicating with other immune cells. However, the underlying mechanism(s) of this process is incompletely understood. DESIGN: FVB/NJ mice were hydrodynamically injected with AKT/Ras and Sleeping Beauty transposon to i...

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Detalles Bibliográficos
Autores principales: Liu, Ningning, Wang, Xiaomei, Steer, Clifford John, Song, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279850/
https://www.ncbi.nlm.nih.gov/pubmed/34706869
http://dx.doi.org/10.1136/gutjnl-2021-324170