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Deletion of activin A in mesenchymal but not myeloid cells ameliorates disease severity in experimental arthritis

OBJECTIVE: The aim of this study was to assess the extent and the mechanism by which activin A contributes to progressive joint destruction in experimental arthritis and which activin A-expressing cell type is important for disease progression. METHODS: Levels of activin A in synovial tissues were e...

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Detalles Bibliográficos
Autores principales: Waltereit-Kracke, Vanessa, Wehmeyer, Corinna, Beckmann, Denise, Werbenko, Eugenie, Reinhardt, Julia, Geers, Fabienne, Dienstbier, Mike, Fennen, Michelle, Intemann, Johanna, Paruzel, Peter, Korb-Pap, Adelheid, Pap, Thomas, Dankbar, Berno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279851/
https://www.ncbi.nlm.nih.gov/pubmed/35418478
http://dx.doi.org/10.1136/annrheumdis-2021-221409