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Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

OBJECTIVE: Although gut dysbiosis is increasingly recognised as a pathophysiological component of metabolic syndrome (MetS), the role and mode of action of specific gut microbes in metabolic health remain elusive. Previously, we identified the commensal butyrogenic Anaerobutyricum soehngenii to be a...

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Detalles Bibliográficos
Autores principales: Koopen, Annefleur, Witjes, Julia, Wortelboer, Koen, Majait, Soumia, Prodan, Andrei, Levin, Evgeni, Herrema, Hilde, Winkelmeijer, Maaike, Aalvink, Steven, Bergman, Jacques J G H M, Havik, Stephan, Hartmann, Bolette, Levels, Han, Bergh, Per-Olof, van Son, Jamie, Balvers, Manon, Bastos, Diogo Mendes, Stroes, Erik, Groen, Albert K, Henricsson, Marcus, Kemper, Ellis Marleen, Holst, Jens, Strauch, Christopher M, Hazen, Stanley L, Bäckhed, Fredrik, De Vos, Willem M, Nieuwdorp, Max, Rampanelli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279853/
https://www.ncbi.nlm.nih.gov/pubmed/34697034
http://dx.doi.org/10.1136/gutjnl-2020-323297