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Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study
OBJECTIVE: Although gut dysbiosis is increasingly recognised as a pathophysiological component of metabolic syndrome (MetS), the role and mode of action of specific gut microbes in metabolic health remain elusive. Previously, we identified the commensal butyrogenic Anaerobutyricum soehngenii to be a...
Autores principales: | Koopen, Annefleur, Witjes, Julia, Wortelboer, Koen, Majait, Soumia, Prodan, Andrei, Levin, Evgeni, Herrema, Hilde, Winkelmeijer, Maaike, Aalvink, Steven, Bergman, Jacques J G H M, Havik, Stephan, Hartmann, Bolette, Levels, Han, Bergh, Per-Olof, van Son, Jamie, Balvers, Manon, Bastos, Diogo Mendes, Stroes, Erik, Groen, Albert K, Henricsson, Marcus, Kemper, Ellis Marleen, Holst, Jens, Strauch, Christopher M, Hazen, Stanley L, Bäckhed, Fredrik, De Vos, Willem M, Nieuwdorp, Max, Rampanelli, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279853/ https://www.ncbi.nlm.nih.gov/pubmed/34697034 http://dx.doi.org/10.1136/gutjnl-2020-323297 |
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