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Polymerases and DNA Repair in Neurons: Implications in Neuronal Survival and Neurodegenerative Diseases
Most of the neurodegenerative diseases and aging are associated with reactive oxygen species (ROS) or other intracellular damaging agents that challenge the genome integrity of the neurons. As most of the mature neurons stay in G0/G1 phase, replication-uncoupled DNA repair pathways including BER, NE...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279898/ https://www.ncbi.nlm.nih.gov/pubmed/35846567 http://dx.doi.org/10.3389/fncel.2022.852002 |