Polymerases and DNA Repair in Neurons: Implications in Neuronal Survival and Neurodegenerative Diseases

Most of the neurodegenerative diseases and aging are associated with reactive oxygen species (ROS) or other intracellular damaging agents that challenge the genome integrity of the neurons. As most of the mature neurons stay in G0/G1 phase, replication-uncoupled DNA repair pathways including BER, NE...

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Detalles Bibliográficos
Autores principales: Li, Xiaoling, Cao, Guanghui, Liu, Xiaokang, Tang, Tie-Shan, Guo, Caixia, Liu, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279898/
https://www.ncbi.nlm.nih.gov/pubmed/35846567
http://dx.doi.org/10.3389/fncel.2022.852002

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