RNA demethylase ALKBH5 regulates hypopharyngeal squamous cell carcinoma ferroptosis by posttranscriptionally activating NFE2L2/NRF2 in an m(6)A‐IGF2BP2‐dependent manner

BACKGROUND: Having emerged as the most abundant posttranscriptional internal mRNA modification in eukaryotes, N6‐methyladenosine (m(6)A) has attracted tremendous scientific interest in recent years. However, the functional importance of the m(6)A methylation machinery in ferroptosis regulation in hy...

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Detalles Bibliográficos
Autores principales: Ye, Jing, Chen, Xiaozhen, Jiang, Xiaohua, Dong, Zhihuai, Hu, Sunhong, Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279968/
https://www.ncbi.nlm.nih.gov/pubmed/35689537
http://dx.doi.org/10.1002/jcla.24514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9279968/
https://www.ncbi.nlm.nih.gov/pubmed/35689537
http://dx.doi.org/10.1002/jcla.24514

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