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Carbapenem antibiotic stress increases bla (KPC) (‐2) gene relative copy number and bacterial resistance levels of Klebsiella pneumoniae

BACKGROUND: The clinical isolation rates of carbapenem‐resistant Klebsiella pneumoniae (CR‐KP) continue to increase. In China, clinical CR‐KP isolates are mainly attributed to the bla (KPC‐2) gene carried on plasmids, and the bla (KPC‐2) copy number correlates with the expression of KPC enzymes, whi...

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Detalles Bibliográficos
Autores principales: Chen, Huimin, Li, Na, Wang, Fang, Wang, Lei, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280016/
https://www.ncbi.nlm.nih.gov/pubmed/35718993
http://dx.doi.org/10.1002/jcla.24519