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TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels

PIEZO2 channels mediate rapidly adapting mechanically activated currents in peripheral sensory neurons of the dorsal root ganglia (DRG), and they are indispensable for light touch and proprioception. Relatively little is known about what other proteins regulate PIEZO2 activity in a cellular context....

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Detalles Bibliográficos
Autores principales: Del Rosario, John Smith, Gabrielle, Matthew, Yudin, Yevgen, Rohacs, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280072/
https://www.ncbi.nlm.nih.gov/pubmed/35819364
http://dx.doi.org/10.1085/jgp.202213164